STUDIES ON EXPERIMENTAL RICKETS

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Studies on Experimental Rickets

Our observations show that young rabbits born of mothers afflicted with Schistosomum japonicum develop typical rickets. Rickets can also be produced if we infect the young, healthy rabbits with the same parasite. It is natural to suppose that the rachitic changes are caused by the parasite itself. Since, however, a similar disease can be produced in the offspring, when the mother is fed on egg ...

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Experimental Rickets in Rats

1. Rachitic bone lesions may be produced in rats by a diet containing an excess of calcium, but deficient in phosphates. 2. Similar lesions follow a diet deficient in calcium, but containing an excess of phosphates. The endochondral lesions, however, are less pronounced. 3. A diet deficient in both calcium and phosphate induces atypical rickets. 4. Inorganic salts other than calcium or phosphat...

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Experimental Rickets in Rabbits

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STUDIES ON EXPERIMENTAL RICKETS. VIII. THE PRODUCTION OF RICKETS BY DIETS LOW IN PHOS- PHORUS AND FAT-SOLUBLE A. BY E. V. McCOLLUM AND NINA SIMMONDS,

In a brief preliminary report’ we described a faulty ration and its effects on t,he skeleton of the growing rat, which corresponded in all essential details to rickets as that disease manifests itself in the skeleton of the human being. The faulty ration in question, No. 3127, was deficient in phosphorus and fat-soluble A.2 In other respects it was, apparently, satisfactorily constituted. It co...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1921

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)86066-5